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effectiveness trial
Studies to assess the effects of treatments can be designed to address one of two broad questions:
"Can this treatment work, give ideal circumstances?" or "Does this treatment work, in the messy circumstances of the real world?"
Those studies that address the first of these questions are referred to as ‘explanatory’, or ‘efficacy’ trials; those that address the second question are referred to as ‘pragmatic’, or’ effectiveness’ trials
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